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Energy metabolism support; Methylation and homocysteine support; Nervous system support
Adults with busy lifestyles who want easy daily B-vitamin support, or individuals with low intake of B-rich foods.
Adults take 2 capsules once daily with 8 ounces of water; may be taken with or without food. If sensitive, try with a meal to improve comfort.
Non-GMO; Soy-Free; Dairy Free; Gluten Free; Contains no listed major allergens in Supplement Facts and other ingredients.
As a coenzyme (FAD/FMNH2), it helps enzymes in energy production and antioxidant recycling in cells.
Caution: High-dose B2 may cause bright yellow urine; this is harmless and due to riboflavin excretion.
As the active form of B6, it supports amino acid metabolism and neurotransmitter synthesis.
Caution: Large amounts of B6 over time may cause nerve tingling or numbness; follow the suggested use.
As the methylated form of folate, it donates methyl groups for homocysteine metabolism and DNA-related processes.
Caution: Folate can mask low vitamin B12 status; consistent B12 intake is important when using folate.
As a methyl donor and cofactor, it supports homocysteine metabolism and red blood cell formation.
Caution: Very high B12 intakes may cause mild acne-like skin changes in some people; discontinue if bothersome.
Acts as a methyl donor to help convert homocysteine to methionine via the BHMT pathway.
Caution: May cause mild digestive discomfort in some individuals; take with water and assess tolerance.
Methylated folate and methylcobalamin provide methyl groups for the methionine cycle, while betaine supports an alternate methylation route via BHMT. Riboflavin-5’-phosphate and pyridoxal-5’-phosphate act as enzyme cofactors that help drive one-carbon and amino acid metabolism, complementing the methyl donors.
Label Warning: Do not exceed the recommended dose. Pregnant or nursing individuals, children under 18, and people with a known medical condition should consult a physician before use. Discontinue use two weeks before surgery. Use caution if you have allergies or sensitivities to any listed ingredients.
Who should be cautious: People taking medications for mood, seizures, or blood pressure may want to consult a healthcare provider due to high-dose B vitamins and betaine. Individuals with kidney issues or a history of kidney stones may use caution with high-dose B vitamins. Those with MTHFR variants who are sensitive to methylated vitamins may prefer to start with a lower amount and discuss with a clinician.
Storage: Store in a cool, dry place.
Many reviewers mention increased energy and clearer focus after consistent use.
Capsules are reported as simple to take without unpleasant flavor or side effects.
A few notes imply results depend on personal factors and may not be the same for everyone.
This product is guaranteed authentic and backed by our easy returns & refunds policy. Details
Magnesium and B vitamins may support energy production and reduce fatigue, promoting overall vitality and well-being.
AI generated. Not medical advice.
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Codeage Methylfolate B Complex+ offers a blend of folate as 5-MTHF, riboflavin vitamin B2, vitamin B6, vitamin B12 in its methylated form, and betaine for a comprehensive vitamin B complex formula. 2-month supply.
Adults take 2 capsules daily, or as recommended by your healthcare practitioner, with 8 ounces of water or your favorite beverage. May be taken with or without food.
Methylcellulose capsule, microcrystalline cellulose, l-leucine.
Made in the USA with globally sourced ingredients.
Do not exceed recommended dose. Pregnant or nursing mothers, children under 18 and individuals with a known medical condition should consult a physician before using this or any dietary supplement. Discontinue use two weeks prior to surgery. Please use caution if you have allergies or sensitivities to any of the listed ingredients.
Store in a cool, dry place. Do not use if product has been opened or tampered with in any way. Keep out of reach of children and pets.
While iHerb strives to ensure the accuracy of its product images and information, some manufacturing changes to packaging and/or ingredients may be pending update on our site. Although items may occasionally ship with alternate packaging, freshness is always guaranteed. We recommend that you read labels, warnings and directions of all products before use and not rely solely on the information provided by iHerb.
| Supplement facts | ||
| Serving Size: 2 Capsules | ||
| Servings Per Container: 60 | ||
| Amount Per Serving | %DV | |
| Riboflavin (as Riboflavin-5'-Phosphate) | 30 mg | 2,308% |
| Vitamin B6 (as Pyridoxal-5'-Phosphate) | 15 mg | 882% |
| Folate (as Quatrefolic® [6S]-5-Methyltetrahydrofolate, Glucosamine Salt) | 1,360 mcg DFE | 340% |
| Vitamin B12 (as Methylcobalamin) | 1,000 mcg | 41,667% |
| Betaine (as Trimethylglycine) | 600 mg | ** |
| **Daily Value (DV) not established. | ||
