AI overview
AI generated. Not medical advice.What it's for
Joint health, cartilage support, connective tissue nutrition, comfortable movement
Who it may fit
Active adults or those with physically demanding routines seeking daily joint structure and comfort support.
Key actives per serving
- Glucosamine Hydrochloride: 1500 mg (1.5 g)
- MSM (methylsulfonylmethane): 1000 mg (1 g)
- Manganese (as manganese glycinate): 5 mg (217% DV)
- Vitamin C (as calcium ascorbate): 100 mg (111% DV)
- Ginger 4:1 Extract (root): 108 mg (equivalent to 432 mg ginger)
How to take
Adults take 3 tablets once daily, preferably with a meal; taking with food may enhance comfort for ginger and MSM.
Diet / Allergen fit
Certified Gluten Free; Wheat Free; Dairy Free; Suitable for Vegans; Kosher Parve; Free of: gluten, wheat, dairy, soy, yeast, sugar, sodium, artificial flavor, sweetener, preservatives, and color; Shellfish-Free
Ingredients explained
Glucosamine Hydrochloride
Glucosamine serves as a building block for glycosaminoglycans in cartilage, which may support joint structure and lubrication.
Caution: Those with shellfish allergies often tolerate vegetarian glucosamine, but check labels and personal tolerance.
MSM (methylsulfonylmethane)
MSM provides bioavailable sulfur used in connective tissue proteins and may support a normal inflammatory response in joints.
Caution: May cause mild digestive discomfort in some people; start with food to reduce stomach upset.
Manganese (as manganese glycinate)
Manganese acts as a cofactor for enzymes involved in cartilage formation and antioxidant defense.
Caution: High intake can be excessive over time; do not combine with multiple high-manganese supplements.
Vitamin C (as calcium ascorbate)
Vitamin C supports collagen synthesis by acting as a cofactor for enzymes that stabilize and cross-link connective tissue proteins.
Caution: May cause mild stomach upset in sensitive individuals; taking with food can help.
Ginger 4:1 Extract (root)
Ginger compounds may modulate inflammatory signaling and support comfortable joint movement.
Caution: May interact with blood-thinning medications; monitor for increased bruising or stomach discomfort.
How they work together
Glucosamine supplies structural building blocks for cartilage, while MSM provides sulfur that is incorporated into connective tissues. Vitamin C and manganese support collagen and cartilage enzyme activity, and ginger adds modulatory effects on inflammatory signaling for overall joint comfort.
Safety and tips
Label Warning: Consult a healthcare practitioner before use if pregnant, nursing, taking any medication (including blood thinners), or have any medical condition. Willow Bark Extract is recognized by the body like aspirin; if you have an aspirin allergy, consult your physician before use. Discontinue use and consult a healthcare practitioner if adverse reactions occur. Not intended for persons under 18.
Who should be cautious: People with aspirin allergy or sensitivity, bleeding concerns, or those using anticoagulants or antiplatelet drugs may need extra caution due to Willow Bark Extract. Individuals with stomach irritation or a history of ulcers may be sensitive to salicylate-containing ingredients. Consult a healthcare provider before use if combining with medications that may interact.
Storage: Store at room temperature.
What customers say
Noticed joint comfort support
Many reviewers felt better joint comfort and function after consistent use.
Gentle on digestion
Users commonly reported no stomach upset or digestive discomfort.
Results may take time
Some customers had not used it long enough to notice changes yet.
iHerb Quality Promise
This product is guaranteed authentic and backed by our easy returns & refunds policy. Details
MSM may support joint health by reducing inflammation and improving flexibility, complementing glucosamine and chondroitin's role in maintaining cartilage.
AI generated. Not medical advice.
Overview
- Since 1947
- Shellfish-Free
- Promotes Healthy Joints
- Supports Comfortable Movement
- Certified Gluten Free
- Wheat & Dairy Free
- Suitable for Vegans
- Kosher Parve
- Dietary Supplement
- OptiMSM®
- Regenasure® Glucosamine
This formulation provides vegetarian-source Glucosamine to nutritionally support joint health. Vitamin C and Manganese are also included to support production of collagen and healthy cartilage compounds. MSM, a natural source of the important mineral sulfur, Ginger Root and White Willow Bark are also included. Collectively, the ingredients in this formulation help to promote healthy joint structure and flexibility, which supports comfortable movement.
Individual results may vary.
Specifications
- First available: 05/2008
-
Shipping weight:
0.37 kg
- Product code: SOL-01315
- UPC: 033984013155
- Package quantity: 120 count
- Dimensions: 12.8 x 6.7 x 6.7 cm , 0.37 kg
Suggested use
As a dietary supplement for adults, take three (3) tablets daily, preferably with a meal, or as directed by a healthcare practitioner.
Other ingredients
Microcrystalline cellulose, vegetable cellulose, silica, vegetable magnesium stearate, vegetable glycerin.
Free of: Gluten, wheat, dairy, soy, yeast, sugar, sodium, artificial flavor, sweetener, preservatives and color.
Warnings
If you are pregnant, nursing, taking medication, including blood thinners, or have any medical condition, please consult your healthcare practitioner before taking any dietary supplement. Willow Bark Extract is a natural ingredient that the body recognizes like aspirin. If you have an allergy to aspirin, please consult your physician before use. Discontinue use and consult your healthcare practitioner if any adverse reactions occur. Not intended for use by persons under the age 18. Keep out of reach of children Store at room temperature. Do not use if outer bottle seal is missing or damaged.
Due to the natural variation of the raw material, tablet color and appearance may vary from batch to batch.
Disclaimer
While iHerb strives to ensure the accuracy of its product images and information, some manufacturing changes to packaging and/or ingredients may be pending update on our site. Although items may occasionally ship with alternate packaging, freshness is always guaranteed. We recommend that you read labels, warnings and directions of all products before use and not rely solely on the information provided by iHerb.
| Supplement facts | ||
| Serving Size: 3 Tablets | ||
| Servings Per Container: 40 | ||
| Amount Per Serving | %DV | |
| Calories | 5 | |
| Total Carbohydrate | 2 g | 1%** |
| Vitamin C (as calcium ascorbate) | 100 mg | 111% |
| Manganese (as manganese glycinate†) | 5 mg | 217% |
| Glucosamine Hydrochloride (vegetarian, shellfish-free) | 1500 mg (1.5 g) | *** |
| MSM (methylsulfonylmethane, OptiMSM®) | 1000 mg (1 g) | *** |
| Ginger 4:1 Extract (Zingiber officinale) (root) (equivalent to 432 mg of Ginger) | 108 mg | *** |
| Willow Bark Extract 5:1 Extract (salix spp.) (bark) (equivalent to 500 mg of Willow Bark) | 100 mg | *** |
| **Percent Daily Values (DV) are based on a 2,000 calorie diet ***Daily Value (DV) not established †Albion International Inc | ||